The Department of Molecular, Cellular and Biomedical Sciences provides an education based on research and scientific information, intended to meet the needs of those interested in the biomedical and molecular/cellular life sciences.
Faculty may submit research here.
Submissions from 1994
Possible clinical applications for direct molecular charge determination by equilibrium electrophoresis, Theresa M. Ridgeway, David B. Hayes, Arthur L. Anderson, John H. Levasseur, Phillip D. Demaine, Burt E. Kenty, and Thomas M. Laue
Testing an FTIR-consistent Model of the Soluble Domain of Human Tissue Factor, J. B. Alexander Ross, C. A. Hasselbacher, T. F. Kumosinski, Gina King, Thomas M. Laue, Arabinda Guha, Yale Nemerson, William H. Konigsberg, Elena Rusinova, and Evan Waxman
Defining Hydrodynamic Shapes by Combination of Ultracentrifugation and Fluorescence Anisotropy Decay, J. B. Alexander Ross, Evan Waxman, William R. Laws, and Thomas M. Laue
Modern analytical ultracentrifugation : Acquisition and interpretation of data for biological and synthetic polymer systems, Todd M. Schuster and Thomas M. Laue
Coiled Coil Molecular Recognition: Directed Solution Assembly of Receptor Ectodomains, Zining Wu, Steven F. Eaton, Thomas M. Laue, Kirk W. Johnson, Theodore R. Sana, and Thomas L. Ciardelli
On Line Data Acquisition for the Rayleigh Interference Optical System of the Analytical Ultracentrifuge, David A. Yphantis, Jeffrey W. Lary, Walter F. Stafford III, S. Liu, Philip H. Olsen, David B. Hayes, Thomas P. Moody, Theresa M. Ridgeway, Daryl A. Lyons, and Thomas M. Laue
Submissions from 1993
A centrifugal separation procedure detects moderate affinity cGMP binding sites in membrane-associated proteins and permeabilized cells., R S. Forget, J E. Martin, and Rick H. Cote
Real-time Interferometry in the Ultracentrifuge, Thomas M. Laue
5-Hydroxytryptophan as a new intrinsic probe for investigating protein-DNA interactions by analytical ultracentrifugation. Study of the effect of DNA on self-assembly of the bacteriophage .lambda. cI repressor, Thomas M. Laue, Donald F. Senear, Steven F. Eaton, and J. B. Alexander Ross
The primary self-assembly reaction of bacteriophage .lambda. cI repressor dimers is to octamer, Donald F. Senear, Thomas M. Laue, J. B. Alexander Ross, Evan Waxman, Steven F. Eaton, and Elena Rusinova
Silk glands of araneid spiders: Selected morphological and physiological aspects, Edward K. Tillinghast and Mark A. Townley
The adhesive glycoprotein of the orb web of Argiope aurantia (Araneae, Araneidae), Edward K. Tillinghast, Mark A. Townley, T. N. Wright, G. Uhlenbruck, and E. Janssen
Inhibition of Escherichia coli chemotaxis by omega-conotoxin, a calcium ion channel blocker, Louis S. Tisa, Baldomero M. Olivera, and Julius Adler
Moult-related changes in ampullate silk gland morphology and usage in the araneid spider Araneus cavaticus, Mark A. Townley, Edward K. Tillinghast, and Nancy A. Cherim
Structural and Functional Characterization of Monomeric Soluble P-Selectin and Comparison with Membrane P-Selectin, Shigeru Ushiyama, Thomas M. Laue, Kevin L. Moore, Harold P. Erickson, and Rodger P. McEver
Human Factor VIIa and its Complex with Soluble Tissue Factor: Evaluation of Asymmetry and Conformational Dynamics by Ultracentrifugation and Fluorescence Anisotropy Decay Methods, Evan Waxman, William R. Laws, Thomas M. Laue, Yale Nemerson, and J. B. Alexander Ross
Submissions from 1992
Retroviral integrase functions as a multimer and can turn over catalytically, K. S. Jones, Jacqueline Coleman, George W. Merkel, Thomas M. Laue, and Anna M. Skalka
On-line Data Acquisition and Analysis from the Rayleigh Interferometer, Thomas M. Laue
Computer-aided Interpretation of Sedimentation Data for Proteins, Thomas M. Laue, B. Shah, Theresa M. Ridgeway, and S. L. Pelletier
Calcium-dependence of the interactions between protein C, thrombin and the elastase fragment of thrombomodulin. Analysis by ultracentrifugation, Philip H. Olsen, Naomi L. Esmon, Charles T. Esmon, and Thomas M. Laue
Structural Comparisons of Meizothrombin and Its Precursor Prothrombin in the Presence or Absence of Procoagulant Membranes, Gang Pei, Thomas M. Laue, Ann Aulabaugh, Dana M. Fowlkes, and Barry R. Lentz
Folding Topology of the Disulfide-Bonded Dimeric DNA-Binding Domain of the Myogenic Determination Factor MyoD, Melissa A. Starovasnik, T. Keith Blackwell, Thomas M. Laue, Harold Weintraub, and Rachel E. Klevit
Fibrous composite structure in a spider silk, D. G. Stubbs, Edward K. Tillinghast, Mark A. Townley, and N. A. Cherim
Calcium ions are involved in Escherichia coli chemotaxis, Louis S. Tisa and Julius Adler
Tissue Factor and its Extracellular Soluble Domain: The Relationship Between Intermolecular Association with Factor VIIa and Enzymatic Activity of the Complex, Evan Waxman, J. B. Alexander Ross, Thomas M. Laue, Arabinda Guha, S. V. Thiruvikraman, T. C. Lin, William H. Konigsberg, and Yale Nemerson
Membrane topology of the ArsB protein, the membrane subunit of an anion-translocating ATPase, Jianhua Wu, Louis S. Tisa, and Barry P. Rosen
Submissions from 1991
A Novel Trypsin Inhibitor from the Hemolymph of the Horseshoe Crab, Limulus polyphemus, Maribeth A. Donovan and Thomas M. Laue
Detection and isolation of proctolin-like immunoreactivity in arachnids: Possible cardioregulatory role for proctolin in the orb-weaving spiders Argiope and Araneus, James R. Groome, Mark A. Townley, Marianne De Tschaschell, and Edward K. Tillinghast
Proteoglycans of Bovine Articular Cartilage. The Effects of Divalent Cations on the Biochemical Properties of Link Protein, Lawrence Rosenberg, Haing U. Choi, L. H. Lang, S. Pal, T. Johnson, D. A. Lyons, and Thomas M. Laue
Comparative study of orb web hygroscopicity and adhesive spiral composition in three araneid spiders, Mark A. Townley, David T. Bernstein, Kathleen S. Gallagher, and Edward K. Tillinghast
Selected aspects of spinning apparatus development in Araneus cavaticus (Araneae, Araneidae), Mark A. Townley, Norman V. Horner, Nancy A. Cherim, Cathy R. Tugmon, and Edward K. Tillinghast
Submissions from 1990
Identification of proctolin in the central nervous system of the horseshoe crab, Limulus polyphemus, James R. Groome, Edward K. Tillinghast, Mark A. Townley, Alex Vetrovs, Winsor H. Watson III, Donald F. Hunt, Patrick R. Griffin, Janice E. Alexander, and Jeffery Shabanowitz
Ultracentrifugation, Thomas M. Laue
Methods for Measuring Size, Molecular Weight and Presence of Subunits, Thomas M. Laue and David G. Rhodes
Relative Helix-forming Tendencies of Nonpolar Amino Acids, S. Padmanabhan, Susan Marqusee, Theresa M. Ridgeway, Thomas M. Laue, and Robert L. Baldwin
Methods for Determining Purity, David G. Rhodes and Thomas M. Laue
A plasmid-encoded anion-translocating ATPase, Barry P. Rosen, Ching-Mei Hsu, Cyrus E. Karkaria, Parjit Kaur, Joshua B. Owolabi, and Louis S. Tisa
Molecular Analysis of an ATP-Dependent Anion Pump, Barry P. Rosen, Ching-Mei Hsu, Cyrus E. Karkaria, Joshua B. Owolabi, and Louis S. Tisa
Identification of the metalloregulatory element of the plasmid-encoded arsenical resistance operon, Michael J. D. San Francisco, Constance L. Hope, Joshua B. Owolabi, Louis S. Tisa, and Barry P. Rosen
Molecular characterization of an anion pump. The ArsB protein is the membrane anchor for the ArsA protein, Louis S. Tisa and Barry P. Rosen
Transport systems encoded by bacterial plasmids, Louis S. Tisa and Barry P. Rosen
Compounds in the droplets of the orb spider's viscid spiral, Fritz Vollrath, Wayne J. Fairbrother, Robert J.P. Williams, Edward K. Tillinghast, David T. Bernstein, Kathleen S. Gallagher, and Mark A. Townley
Submissions from 1989
Cyclic GMP levels and membrane current during onset, recovery, and light adaptation of the photoresponse of detached frog photoreceptors., Rick H. Cote, Grant D. Nicol, Sheila A. Burke, and M Deric Bownds
Ultracentrifugation, Thomas M. Laue
Direct determination of macromolecular charge by equilibrium electrophoresis, Thomas M. Laue, Andrea L. Hazard, Theresa M. Ridgeway, and David A. Yphantis
Calcium-dependent structural changes in bovine blood coagulation factor Va and its subunits, Thomas M. Laue, Ruiliang Lu, Ute C. Krieg, Charles T. Esmon, and Arthur E. Johnson
Interaction of clotting factor V heavy chain with prothrombin and prethrombin 1 and role of activated protein C in regulating this interaction: analysis by analytical ultracentrifugation, Elizabeth A. Luckow, Daryl A. Lyons, Theresa M. Ridgeway, Charles T. Esmon, and Thomas M. Laue
Characterization of guanylate cyclase in squid photoreceptors., Phylis R. Robinson and Rick H. Cote
Identification of the membrane component of the anion pump encoded by the arsenical resistance operon of R-factor R773, Michael J. D. San Francisco, Louis S. Tisa, and Barry P. Rosen
The molecular weight and oligomerization of rabbit thrombomodulin as assessed by sedimentation equilibrium, Paul T. Winnard, Charles T. Esmon, and Thomas M. Laue
Submissions from 1988
Evidence for adenylate nucleotide transport (ATP-ADP translocation) in vesicles of Frankia sp. strain EAN1pec, Louis S. Tisa and J. C. Ensign
Orb web recycling in Araneus cavaticus (Araneae, Araneidae) with an emphasis on the adhesive spiral component, GABamide, Mark A. Townley and Edward K. Tillinghast
Submissions from 1987
Evidence for the presence of GABamide in the webs of orb weaving spiders, Edward K. Tillinghast, R. J. Huxtable, Winsor H. Watson III, and Mark A. Townley
Chemistry, physical properties and synthesis of Araneidae orb webs, Edward K. Tillinghast and Mark A. Townley
Comparative physiology of nitrogenase activity and vesicle development for Frankia strains CpI1, ACN1AG, EAN1pec and EUN1f, Louis S. Tisa and J. C. Ensign
Formation and Regeneration of Protoplasts of the Actinorhizal Nitrogen-Fixing Actinomycete Frankia, Louis S. Tisa and J. C. Ensign
Isolation and nitrogenase activity of vesicles from Frankia sp. strain EAN1pec, Louis S. Tisa and J. C. Ensign
The calcium requirement for functional vesicle development and nitrogen fixation by Frankia strains EAN1pec and CpI1, Louis S. Tisa and J. C. Ensign
Submissions from 1986
Changes in cGMP concentration correlate with some, but not all, aspects of the light-regulated conductance of frog rod photoreceptors., Rick H. Cote, Grant D. Nicol, Sheila A. Burke, and M Deric Bownds
cGMP influences guanine nucleotide binding to frog photoreceptor G-protein., Phylis R. Robinson, Monte J. Radeke, Rick H. Cote, and M Deric Bownds
The independent regulation of protein synthesis in the major ampullate glands of Araneus cavaticus (Keyserling), Edward K. Tillinghast and Mark A. Townley
Submissions from 1985
Direct Determination of the Association Constant Between Elongation Factor Tu-GTP and Amino Acyl-tRNA Using Fluorescence, Julie K. Abrahamson, Thomas M. Laue, David L. Miller, and Arthur E. Johnson
Characterization of vesicles isolated from Frankia isolate EAN1pec, Louis S. Tisa
Characterization of vesicles isolated from Frankia srain EAN1pec, Louis S. Tisa
Formation and regeneration of Frankia protoplasts, Louis S. Tisa
Submissions from 1984
Rapid Precision Interferometry for the Analytical Ultracentrifuge. II. A Laser Controller Based on a Rate-Multiplying Circuit, Ian Anderson, Thomas M. Laue, and David A. Yphantis
Light-induced decreases in cGMP concentration precede changes in membrane permeability in frog rod photoreceptors., Rick H. Cote, Michael S. Biernbaum, Grant D. Nicol, and M Deric Bownds
The Structure of Bovine Blood Coagulation Factor Va. Determination of Subunit Associations, Molecular Weights and Asymmetries by Analytical Ultracentrifugation, Thomas M. Laue, Arthur E. Johnson, Charles T. Esmon, and David A. Yphantis
Rapid precision interferometry for the analytical ultracentrifuge: III. Determination of period of rotation, frequency of rotation, and elapsed time, Thomas M. Laue, David A. Yphantis, and David G. Rhodes
Water extraction by the major ampullate duct during silk formation in the spider, Argiope aurantia Lucas, Edward K. Tillinghast, S. F. Chase, and Mark A. Townley
Submissions from 1983
Structural Changes Required for Activation of Protein C Are Induced by Ca2 Binding to a High Affinity Site That Does Not Contain y-Carboxyglutamic Acid, Arthur E. Johnson, Naomi L. Esmon, Thomas M. Laue, and Charles T. Esmon
Rapid precision interferometry for the analytical ultracentrifuge: I. A laser controller based on a phase-lock-loop circuit, Thomas M. Laue, Richard A. Domanik, and David A. Yphantis
Studies of growth and morphology of Frankia strains EAN1pec, EuI1c, CpI1, and ACN1AG, Louis S. Tisa, Mark McBride, and J. C. Ensign
Submissions from 1982
Photometric immersion refractometry of bacterial spores, P. Gerhardt, T. C. Beaman, T. R. Corner, J. T. Greenamyre, and Louis S. Tisa
Wet and dry bacterial spore densities determined by buoyant sedimentation, Louis S. Tisa, T. Koshikawa, and P. Gerhardt
Submissions from 1981
Formulation of the general rate equation for subunit flux at steady-state., Rick H. Cote, Charles F. Anderson, and Gary G. Borisy
Head-to-tail polymerization of microtubules in vitro., Rick H. Cote and Gary G. Borisy
ATP-Induced Formation of an Associated Complex Between Microtubules and Neurofilaments, M. S. Runge, Thomas M. Laue, David A. Yphantis, M. R. Lifsics, A. Saito, M. Altin, K. Reinke, and R. C. Williams Jr.
Effect of water activity on the heat resistance of vegetative cells of Bacillus megaterium, Louis S. Tisa
Isopycnic density gradient determination of wet and dry densities of representative bacterial spore types, Louis S. Tisa
Photometric immersion refractory of bacterial spores, Louis S. Tisa
The effect of water activity of core and cortex on the heat resistance of bacterial spores, Louis S. Tisa
Submissions from 1980
Expression of glycosidase activities during germination of Dictyostelium discoideum spores, Louis S. Tisa and David A. Cotter
Submissions from 1979
The physiological effects of restrictive environmental conditions on Dictyostelium discoideum spore germination, David A. Cotter, Frederick J. Garnish, and Louis S. Tisa
The expression of acid and alkaline phosphatase activities during germination of Dictyostelium discoideum spores, Louis S. Tisa
Trehalase expression during the germination of three resting stages of the dictyosteliaceae, Louis S. Tisa and David A. Cotter
Submissions from 1977
Release of Escherichia coli DNA from membrane complexes by single-strand endonucleases., M Abe, W G. Hendrickson, D H. Boyd, P Clifford, Rick H. Cote, and M Schaechter