Continuous administration of 5-hydroxytryptamine alters cellular immunity in chickens

Abstract

1. 5-Hydroxytryptamine administered continuously through osmotic pumps altered the PHA wattle response and in vitro leukocyte capillary tube migration in UNH 105 chickens.

2. Administration of 100 ng/hr 5-hydroxytryptamine for 48 hr significantly suppressed the PHA wattle response.

3. In vitro leukocyte migration was significantly enhanced by 72 hr exposure to 5-hydroxytryptamine at a dose of 100 ng/hr.

Publication Date

1989

Journal Title

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology

Publisher

Elsevier

Digital Object Identifier (DOI)

10.1016/0742-8413(89)90105-9

Scientific Contribution Number

1620

Document Type

Article

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