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Abstract
Chemokines are small Molecular weight peptides responsible for adhesion, activation, and recruitment of leukocytes into tissues. Leukocytes are thought to influence follicular atresia, ovulation, and luteal function. Many studies in recent years have focused attention on the characterization of leukocyte populations within the ovary, the importance of leukocyte-ovarian cell interactions, and more recently, the mechanisms of ovarian leukocyte recruitment. Information about the role of chemokines and leukocyte trafficking (chemotaxis) during ovarian function is important to understanding paracrine-autocrine relationships shared between reproductive and immune systems. Recent advances regarding chemokine expression and leukocyte accumulation within the ovulatory follicle and the corpus luteum are the subject of this mini-review.
Department
Molecular, Cellular and Biomedical Sciences
Publication Date
11-10-2003
Journal Title
Reproductive Biology and Endocrinology
Publisher
BioMed Central
Document Type
Article
Recommended Citation
Townson, David H. and Liptak, Amy R., "Chemokines in the corpus luteum: implications of leukocyte chemotaxis" (2003). Reproductive Biology and Endocrinology. 1.
https://scholars.unh.edu/mcbs_facpub/1
Rights
© 2003 Townson and Liptak; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.