Endothelial-Dependent Flow-Mediated Dilation in African Americans With Masked-Hypertension
Abstract
Office-blood pressure (BP) measurements alone overlook a significant number of individuals with masked-hypertension (office-BP: 120/80–139/89mmHg and 24-h ambulatory BP monitoring (ABPM) daytime ≥135/85mmHg or night-time ≥120/70mmHg). Diminished endothelial function contributes to the pathogenesis of hypertension. To better understand the pathophysiology involved in the increased cardiovascular (CV) disease risk associated with masked-hypertension, we estimated the occurrence, assessed the endothelial function, compared plasma levels of inflammatory markers, white blood cell count (WBC count), tumor necrosis factor-α (TNF-α), and high sensitivity C-reactive protein (hsCRP) and examined the possible relationship between endothelial function and inflammatory markers in apparently healthy prehypertensive (office-BP: 120/80–139/89mmHg) African Americans.
Department
Kinesiology
Publication Date
10-1-2011
Journal Title
American Journal of Hypertension
Digital Object Identifier (DOI)
Document Type
Article
Recommended Citation
Veerabhadrappa P, Diaz KM, Kashem AM, Crabbe DL, Feairheller DL, Sturgeon KM, Williamson ST, Brown MD. Endothelial-Dependent Flow-Mediated Dilation in African Americans with Masked Hypertension. American Journal of Hypertension. 24(10), 1102-1107. 2011.
Rights
© 2011 by the American Journal of Hypertension, Ltd.