https://dx.doi.org/10.1016/0024-3205(89)90317-2">
 

Biosynthetic arginine decarboxylase in phytopathogenic fungi.

Abstract

It has been reported that while bacteria and higher plants possess two different pathways for the biosynthesis of putrescine, via ornithine decarboxylase (ODC) and arginine decarboxylase (ADC); the fungi, like animals, only use the former pathway. We found that contrary to the earlier reports, two of the phytopathogenic fungi ( and ) contain significant levels of ADC activity with very little ODC. The ADC in these fungi has high pH optimum (8.4) and low Km (0.237 mM for . , 0.103 mM for . ), and is strongly inhibited by α-difluoromethylarginine (DFMA), putrescine and spermidine, further showing that this enzyme is probably involved in the biosynthesis of polyamines and not in the catabolism of arginine as in . The growth of these fungi is strongly inhibited by DFMA while α-difluoromethylornithine (DFMO) has little effect.

Department

Biological Sciences

Publication Date

2-22-1989

Journal Title

Life sciences

Publisher

Elsevier BV

Digital Object Identifier (DOI)

https://dx.doi.org/10.1016/0024-3205(89)90317-2

Document Type

Article

Rights

Copyright © 1989 Published by Elsevier Inc.

Share

COinS