Preparation of 1,4-Dioxenes from α-Diazo-β-Keto Esters
Abstract
A novel preparation of 1,4-dioxenes is reported in which a rhodium carbenoid generated from an α-diazo-β-ketoester reacts with a 1,2-diol. Insertion of the carbenoid into the O-H bond followed by hemiacetal formation and acid-catalyzed dehydration generates the targeted 1,4-dioxene.
Department
Chemistry
Publication Date
1-1-1999
Journal Title
Heterocycles
Publisher
The Japan Institute of Heterocyclic Chemistry
Digital Object Identifier (DOI)
10.3987/COM-98-8317
Document Type
Article
Recommended Citation
Preparation of 1,4-Dioxenes from a-Diazo-b-Keto Esters, Hilgenkamp, R.; Brogan, J. B.; Zercher, C. K.; Heterocycles 1999, 51, 1073-1078.
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