Ylide-Mediated Bis-Cyclopropane Formation: A Reversal in Substrate-Mediated Facial Selectivity
Abstract
The substrate-based stereocontrol observed in the sulfur ylide mediated cyclopropanation of cis-β-cyclopropyl-α,β-unsaturated esters is complementary to that observed with zine-carbenoids. The selectivity for preparation of the cis-syn-trans-bis-cyclopropane, although modest, is superior to previous substrate and reagent-mediated processes.
Department
Chemistry
Publication Date
11-11-1996
Journal Title
Tetrahedron Letters
Publisher
Elsevier
Digital Object Identifier (DOI)
10.1016/0040-4039(96)01907-7
Document Type
Article
Recommended Citation
Ylide-Mediated Bis-Cyclopropane Formation: A Reversal in Substrate-Mediated Facial Selectivity, Cebula, R. E. J., Hanna, M. R., Theberge, C. R., Verbicky, C. A., Zercher, C. K., Tetrahedron Lett. 1996, 37, 8341-8344.
Rights
Copyright © 1996, Elsevier
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