Escherichia coli chemotaxis was inhibited by omega-conotoxin, a calcium ion channel blocker. With Tris-EDTA-permeabilized cells, nanomolar levels of omega-conotoxin inhibited chemotaxis without loss of motility. Cells treated with omega-conotoxin swam with a smooth bias, i.e., tumbling was inhibited.
Molecular, Cellular and Biomedical Sciences
Journal of Bacteriology
American Society for Microbiology
Digital Object Identifier (DOI)
Tisa, L.S., B. Olivera, and J. Adler. 1993. Inhibition of Escherichia coli chemotaxis by ?-conotoxin, a calcium channel blocker. J. Bacteriol. 175:1235-1238.