Endothelial-Dependent Flow-Mediated Dilation in African Americans With Masked-Hypertension
Office-blood pressure (BP) measurements alone overlook a significant number of individuals with masked-hypertension (office-BP: 120/80–139/89mmHg and 24-h ambulatory BP monitoring (ABPM) daytime ≥135/85mmHg or night-time ≥120/70mmHg). Diminished endothelial function contributes to the pathogenesis of hypertension. To better understand the pathophysiology involved in the increased cardiovascular (CV) disease risk associated with masked-hypertension, we estimated the occurrence, assessed the endothelial function, compared plasma levels of inflammatory markers, white blood cell count (WBC count), tumor necrosis factor-α (TNF-α), and high sensitivity C-reactive protein (hsCRP) and examined the possible relationship between endothelial function and inflammatory markers in apparently healthy prehypertensive (office-BP: 120/80–139/89mmHg) African Americans.
American Journal of Hypertension
Digital Object Identifier (DOI)
Veerabhadrappa P, Diaz KM, Kashem AM, Crabbe DL, Feairheller DL, Sturgeon KM, Williamson ST, Brown MD. Endothelial-Dependent Flow-Mediated Dilation in African Americans with Masked Hypertension. American Journal of Hypertension. 24(10), 1102-1107. 2011.
© 2011 by the American Journal of Hypertension, Ltd.