NADPH Oxidase p22phox Gene Polymorphisms and Oxidative Stress Responses to Exercise Training in Pre and Stage 1 Hypertensives
Oxidative stress that is mediated through NADPH oxidase activity plays a role in the pathology of hypertension, and aerobic exercise training reduces NADPH oxidase activity. The involvement of genetic variation in the p22phox (CYBA) subunit genes in individual oxidative stress responses to aerobic exercise training has yet to be examined in Pre and Stage 1 hypertensives.
Medicine & Science in Sports & Exercise
Digital Object Identifier (DOI)
Feairheller DL, Park JY, Ellis T, Basu S, Hagberg JM, Brown MD, Fenty-Stewart N. NADPH Oxidase p22phox Gene Polymorphisms and Oxidative Stress Responses to Exercise Training in Pre and Stage 1 Hypertensives. Medicine & Science in Sports & Exercise. 41, 1421-1428. 2009.