Translational Approach to Understanding Endothelial Adaptations to Exercise
PURPOSE: To examine whether the effects of an XT program on human plasma oxidative stress levels and endothelial function marker, nitric oxide (NO), can also be measured in human umbilical vein endothelial cells (HUVECs) using laminar shear stress (LSS) as an exercise mimetic. A LSS stimulus on HUVECs in vitro can represent the increased blood flow that accompanies aerobic exercise, and this model may help identify in vivo molecular adaptations to exercise.
Medicine & Science in Sports & Exercise
Digital Object Identifier (DOI)
Feairheller DL, Sturgeon KM, Kim B, Diaz KM, Williamson S, Veerabhadrappa P, Kretzschmar J, Park JY, Brown MD. Translational Approach to Understanding Endothelial Adaptations to Exercise. Medicine & Science in Sports & Exercise. 43:5. Supp. 2011
© 2011 American College of Sports Medicine