In Vitro Shear Stress Responses of Endothelin-1 in African American and Caucasian HUVECs
Higher levels of plasma Endothelin-1 (ET1), a potent vasoconstrictor, have been reported in African Americans (AA) when compared to Caucasians (CA). However, this racial difference has never been considered when investigating the endothelin system at the cell level.
PURPOSE: To determine the effects of laminar shear stress (LSS), which mimics the exercise shear stress on the endothelium, in vitro and the effects of aerobic exercise training on the endothelin system in vivo.
Medicine & Science in Sports & Exercise
Digital Object Identifier (DOI)
Kretzschmar J, Feairheller DL, Park JY, Kim B, Sturgeon KM, Diaz KM, Williiamson ST, Veerabhadrappa P, Ling C, Brown MD. In Vitro Shear Stress Responses of Endothelin-1 in African American and Caucasian HUVECs. Medicine & Science in Sports & Exercise. 43:5. Supp. 2011.
© 2011 American College of Sports Medicine