Age-related variability in cortical activity during language processing
Purpose: The present study investigated the extent of cortical activity during overt picture naming using functional magnetic resonance imaging (fMRI).
Method: Participants comprised 20 healthy, adult participants with ages ranging from 20 to 82 years. While undergoing fMRI, participants completed a picture-naming task consisting of 60 high-frequency nouns.
Results: Linear regression analysis revealed a positive relationship between age and cortical activation intensity in Broca’s and Wernicke’s areas as well as the right-hemisphere homologue of Broca’s area. In contrast, neural activity in the anterior cingulate gyrus, an area thought to be involved in attentional processing, did not increase as a function of age.
Conclusions: These findings suggest age-related increases in cortical activation during simple language tasks, such as picture naming, in brain areas typically associated with language processing.
Communication Sciences and Disorders
Journal of Speech, Language, and Hearing Research
American Speech-Language-Hearing Association
Digital Object Identifier (DOI)
Fridriksson, J., Morrow, K.L., Moser, D., Baylis, G.C. (2006). Age related variability in cortical activity during language processing. Journal of Speech-Language-Hearing Research, 49(4), 690-697. [PMID: 16908869].