Tandem Chain Extension-Homoenolate Formation: The Formation of α-Methylated-γ-Keto Esters
Abstract
A tandem chain extension−homoenolate formation reaction is described. The treatment of β-keto esters with the Furukawa reagent followed by exposure to a catalytic amount of trimethylsilyl chloride provides access to an ester homoenolate.
Department
Chemistry
Publication Date
9-1-2001
Journal Title
Organic Letters
Publisher
American Chemical Society
Digital Object Identifier (DOI)
10.1021/ol016485t
Document Type
Article
Recommended Citation
Tandem Chain Extension-Homoenolate Formation: The Formation of a-Methylated-g-Keto Esters, Hilgenkamp, R., Zercher, C. K. Org. Lett. 2001, 3, 3037-3040.
Rights
Copyright © 2001, American Chemical Society
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