A Divergent Diastereoselective Approach to Bicyclopropanes

Abstract

The diastereoselective cyclopropanation of three stereoisomerically unique vinylcyclopropanes was studied. The selective preparation of six stereoisomeric bicyclopropanes was accomplished by an iterative reagent-controlled process. With the exception of the cis-syntrans-bicyclopropane, all isomers can be prepared in a diastereomeric excess of greater than 5:1.

Department

Chemistry

Publication Date

7-1-1995

Journal Title

Tetrahedron Letters

Publisher

Elsevier

Digital Object Identifier (DOI)

10.1016/0040-4039(95)01081-R

Document Type

Article

Rights

Copyright © 1995, Elsevier

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