Characterization and distribution of FMRFamide immunoreactivity in the rat central nervous system

Authors

Winsor H. Watson III, University of New Hampshire, DurhamFollow
Thomas L. O'Donohue, National Institute of Health
John F. Bishop, National Institute of Health
Bibie M. Chronwall, National Institute of Health

Abstract

FMRFamide immunoreactive material (irFMRFamide) was studied in rat brain and gastrointestinal tract. Highest irFMRFamide concentrations were found in tissues of the gastrointestinal tract and, in the brain, highest concentrations were found in the hippocampus, midbrain, brainstem and hypothalamus. High pressure liquid chromatographic characterization of irFMRFamide demonstrated that the immunoreactive material in brain, pancreas and duodenum was different from molluscan FMRFamide but it was also distinct from any known neuropeptide.

Department

Jackson Estuarine Laboratory, Biological Sciences

Publication Date

5-1-1984

Journal Title

Peptides

Publisher

Elsevier

Digital Object Identifier (DOI)

https://doi.org/10.1016/0196-9781(84)90087-1

Document Type

Article

Rights

© 1984 Published by Elsevier Inc.

Recommended Citation

O’Donohue, T. L., J. F. Bishop, B. M. Chronwall, J. Groome and W. H. Watson III. 1984. Characterization and distribution of FMRFamide immunoreactivity in the rat Central Nervous System. Peptides 5: 563-568. https://doi.org/10.1016/0196-9781(84)90087-1