Age-related variability in cortical activity during language processing
Purpose: The present study investigated the extent of cortical activity during overt picture naming using functional magnetic resonance imaging (fMRI).
Method: Participants comprised 20 healthy, adult participants with ages ranging from 20 to 82 years. While undergoing fMRI, participants completed a picture-naming task consisting of 60 high-frequency nouns.
Results: Linear regression analysis revealed a positive relationship between age and cortical activation intensity in Broca’s and Wernicke’s areas as well as the right-hemisphere homologue of Broca’s area. In contrast, neural activity in the anterior cingulate gyrus, an area thought to be involved in attentional processing, did not increase as a function of age.
Conclusions: These findings suggest age-related increases in cortical activation during simple language tasks, such as picture naming, in brain areas typically associated with language processing.
Journal of Speech, Language, and Hearing Research
American Speech-Language-Hearing Association
Digital Object Identifier (DOI)
Fridriksson, J., Morrow, K.L., Moser, D., Baylis, G.C. (2006). Age related variability in cortical activity during language processing. Journal of Speech-Language-Hearing Research, 49(4), 690-697. [PMID: 16908869].