Title

Formation of β-Substituted γ-Keto Esters via Zinc Carbenoid-Mediated Chain Extension

Abstract

The conversion of β-keto esters into β-methylated γ-keto esters can be achieved through treatment with zinc carbenoids derived­ from 1,1-diiodoethane. The incorporation of a β-phenyl substituent is also possible through treatment with diiodotoluene

Publication Date

1-1-2007

Journal Title

Synthesis

Publisher

Georg Thieme Verlag Stuttgart

Digital Object Identifier (DOI)

10.1055/s-2007-965886

Document Type

Article

Rights

© Georg Thieme Verlag Stuttgart · New York