Title

Preparation of 1,4-Dioxenes from α-Diazo-β-Keto Esters

Abstract

A novel preparation of 1,4-dioxenes is reported in which a rhodium carbenoid generated from an α-diazo-β-ketoester reacts with a 1,2-diol. Insertion of the carbenoid into the O-H bond followed by hemiacetal formation and acid-catalyzed dehydration generates the targeted 1,4-dioxene.

Publication Date

1-1-1999

Journal Title

Heterocycles

Publisher

The Japan Institute of Heterocyclic Chemistry

Digital Object Identifier (DOI)

10.3987/COM-98-8317

Document Type

Article