Diamond electrodes for neurodynamic studies in Aplysia californica
As part of an ongoing effort to demonstrate that diamond is a versatile electrode material for biological applications, we present our progress in the development of diamond electrodes for the study of neurodynamics in an animal model, Aplysia californica. Diamond provides a unique opportunity to integrate neural stimulation and sensing in the same implantable device. Data from several parallel studies are presented: in vitro measurement of serotonin concentration, measurement of electrical activity, and neural stimulation. Using diamond microelectrodes, changes of the Aplysia californica's feeding patterns are being studied as a function of concentration of serotonin, which can act as a neuromodulator of feeding behavior.
Diamond and Related Materials
Digital Object Identifier (DOI)
Jeffrey M. Halpern, Songtao Xie, Greg P. Sutton, Bryan T. Higashikubo, Cynthia A. Chestek, Hui Lu, Hillel J. Chiel, Heidi B. Martin, Diamond electrodes for neurodynamic studies in Aplysia californica, Diamond and Related Materials, Volume 15, Issues 2–3, February–March 2006, Pages 183-187, ISSN 0925-9635, http://dx.doi.org/10.1016/j.diamond.2005.06.039.